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Sculptra vs Profhilo: Which Injectable Treatment Is Right for You in Singapore?


If you're looking for non-surgical skin rejuvenation, you've probably come across Sculptra and Profhilo-two powerful injectable treatments that improve skin quality, firmness, and overall youthfulness. While they might seem similar, they work in different ways and offer different benefits. At Shine Dermatology, we often get asked: "Should I go for Sculptra or Profhilo?" In this article, we break down the key differences to help you decide which treatment suits your needs best.

What Is Sculptra?

Sculptra is a biostimulatory injectable made from poly-L-lactic acid (PLLA). Unlike traditional fillers, it doesn't instantly add volume. Instead, it stimulates your body to produce natural collagen over time, restoring volume gradually and improving skin texture from within.

How it works: PLLA particles are injected into the deeper layers of the skin, triggering fibroblasts to create new collagen. Over several weeks, this leads to firmer, plumper skin that looks naturally refreshed.

Key benefits of Sculptra:

  • Long-lasting collagen stimulation (up to 2 years)
  • Lifts and restores facial volume naturally
  • Improves skin firmness and elasticity
  • Gradual and natural-looking results
  • Suitable for deeper wrinkles and sagging

What Is Profhilo?

Profhilo is an injectable treatment that delivers ultra-pure hyaluronic acid (HA) beneath the skin. It's not a filler and not a skinbooster it's in a category of its own. Profhilo spreads evenly under the skin to deeply hydrate, stimulate collagen and elastin, and improve skin quality.

How it works: Profhilo contains one of the highest concentrations of HA on the market. Once injected at strategic BAP (Bio Aesthetic Points), it spreads beneath the skin to provide deep hydration and bio-remodelling.

Key benefits of Profhilo:

  • Intense hydration from the inside out
  • Smoother, tighter, more radiant skin
  • Minimal downtime
  • Ideal for dull, dehydrated, or sagging skin
  • Suitable for all skin types, especially in humid climates like Singapore

Sculptra vs Profhilo: A Side-by-Side Comparison

Feature Sculptra Profhilo
Main Ingredient Poly-L-lactic acid (PLLA) Hyaluronic Acid (HA)
Primary Effect Collagen stimulation and volume restoration Deep hydration and skin remodelling
Onset of Results Gradual (4-12 weeks) Visible in 1-2 weeks
Number of Sessions 2-3 sessions, spaced 4-6 weeks apart 2 sessions, 4 weeks apart
Longevity of Results Up to 2 years 6-9 months
Best For Volume loss, sagging skin, deep wrinkles Dehydrated skin, fine lines, skin laxity
Treatment Areas Cheeks, temples, jawline, nasolabial folds Face, neck, décolletage, hands
Downtime Mild swelling or bruising for a few days Minimal swelling, no downtime

Who Should Choose Sculptra?

Sculptra is ideal if you:

  • Have noticeable facial volume loss
  • Want a long-term solution for collagen loss
  • Prefer subtle, natural-looking changes over time
  • Are in your 30s to 60s and want to address signs of aging at a deeper level
  • Want to lift the cheeks, temples, or jawline without surgery

What to expect:

  • Week 1: Mild swelling and possible bruising
  • Week 4: Early collagen stimulation begins
  • Week 8-12: Skin appears firmer, lifted, and more youthful

Who Should Choose Profhilo?

Profhilo may be right for you if you:

  • Have tired, dull, or crepey skin
  • Want an instant glow-up with added hydration
  • Prefer a quick and simple treatment with minimal downtime
  • Are in your 20s to 50s, either as prevention or early anti-aging care
  • Want to improve skin tone and elasticity across larger areas

What to expect:

  • Day 1: Mild bumps at injection sites (usually resolve within 24 hours)
  • Week 1: Hydrated, plumper-looking skin
  • Week 4-6: Firmer, more radiant, and smoother skin

Can You Combine Sculptra and Profhilo?

Absolutely! At Shine Dermatology, many patients benefit from a customised injectable treatment plan that combines the collagen-stimulating power of Sculptra with the hydrating, skin-tightening effects of Profhilo.

Example combination treatment:

  • Month 1: Sculptra session 1
  • Month 2: Profhilo session 1
  • Month 3: Sculptra session 2
  • Month 4: Profhilo session 2

This approach delivers both lift and glow for comprehensive rejuvenation.

Safety, Pain, and Aftercare

Both treatments are safe when administered by a trained dermatologist.

Pain Level: Mild. Most patients describe it as a small pinch or pressure. Topical numbing cream is applied before treatment.

Aftercare Tips:

  • Avoid alcohol and strenuous exercise for 24 hours
  • No facials or massages for one week
  • Use gentle, hydrating skincare
  • Apply sunscreen daily to protect the skin

Why Choose Shine Dermatology for Your Injectable Treatments?

  • MOH-accredited dermatologists
  • Personalised treatment plans
  • Safe, evidence-based products
  • Premium care in a calm, welcoming environment
  • Trusted by patients across Singapore for natural, long-lasting results

Book a Consultation Today

Whether you're considering Sculptra, Profhilo, or a combination of both, our team at Shine Dermatology is here to guide you. Let's work together to achieve your skin goals with confidence.

📍 Conveniently located in Singapore

🗓 Flexible appointments available

📞 Book your consultation now

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